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Articles

03 Oct

Reactive Oxygen Species

  • By Zach Nasr
  • In Articles, Food and Supplements for Optimal Brain Function
  • 0 comment

What Can Oxidative Damage Do to My Cells?

There has been a lot of talk in the health world lately about free radicals, and how they cause many diseases. Reactive oxygen species (ROS) are a particularly reactive and damaging type of free radical.
Free radicals are highly reactive compounds that have one or more unpaired electron which means that they are trying to bond with something else to become stable.

Antioxidant Balance

Antioxidants are simply electron donors that can neutralize the oxidants hence their name. ROS can be dangerous because they can create a chain reaction that can eventually lead to the death of a cell (apoptosis/necrosis).
This chain reaction is often called oxidative stress or oxidative damage. This kind of damage can cause damage to our DNA, and to our cellular structure.

The Effects of Reactive Oxygen Species on Nutrients, and Cells

The irony is that oxygen is required for human life, but some forms of ROS that are often produced by normal cell metabolism can cause damage to carbohydrates, fats, proteins, DNA, RNA, and eventually entire cells.
Our cells have little factories (mitochondria) in them that produce little batteries (adenosine triphosphate/ATP) that store electricity (as electrons) for later use.
Read our Full Article on ATP here to learn how to boost cellular energy.

Superoxide Dismutase (SOD)


As our mitochondria charge up these little batteries sometimes they make a slight build up of metabolic toxins like ROS such as hydrogen peroxide and superoxide.
We naturally have enzymes like catalase, and superoxide dismutase (SOD) that make these ROS neutral.
The problems only arise when the ROS get out of control. Herbs like chaga mushrooms that raise SOD can help manage oxidative stress levels.

Reactive Oxygen Species and Injuries

Many injuries can create extra ROS like not getting enough blood flow to an area of the body (called ischemia), or too much blood flow coming in all at once after there has been a lack of blood flow (called reperfusion).
These types of injuries often happen after a traumatic brain injury (TBI), a stroke, or even a heart attack.
Many studies have shown that many external toxins like cigarette smoke, radiation, certain drugs, pesticides, and many environmental pollutants can create free radicals and ROS.

Free Radicals and Degenerative Illness

Free radicals and the damage they cause has been cited as one of the key factors in many disease processes such as cancer, Alzheimer’s, atherosclerosis, and many more diseases.
There are also many natural cellular processes that can increase free radicals like ROS such as exercise, mitochondrial metabolism, inflammation, and even normal immune function.

They are not “bad” on their own as they are a normal part of biology.
The key is to keep them in balance.

When Can My ROS Be Too High?

If you have recently been injured, experienced prolonged periods of stress, or exposed to toxins and environmental pollutants, then chances are your free radical levels and perhaps even your ROS levels are higher than they should be.
That being said, ROS are required to help send signals to our body about how things are going in each mitochondria and in each cell in our bodies so blasting away all of the free radicals in your body all the time is not necessarily the answer to all of life’s problems.

When Can ROS Be a Good Thing?

For example, if we have an infection, then our body uses inflammation caused by free radicals like ROS to tell our white blood cells (particularly leukocytes and T cells) to go and attack whatever is there.
The problems arise when we have chronic inflammation, and chronically high levels of free radicals which will eventually cause damage to our cells and the nutrients that they need to maintain themselves.

Damage to Enough Cells can Damage an Entire Organ or Body Part

In the case of mitochondria, if they begin producing too many ROS, then proteins on the surface of the mitochondria (called Bcl-2) will detect this damage and eventually punch holes in the mitochondria (with the help of a protein called Bax) and this causes cytochrome c to leak out of the mitochondria.
Simply put, this starts a chain reaction that breaks down the mitochondria, and if left unchecked, this can cause the entire cell to break down (apoptosis/necrosis).
This is how the process of oxidative damage can lead to the destruction of entire cells, and even large portions of certain organs like our livers, brains, and hearts.

We have multi-layered defense system for removing free radicals. This chart shows why dietary antioxidants are so important, and it shows the importance of some of these supplements below.

 

What Are Some Supplements That Can Help with ROS?

The good news is that there are supplements that have been proven to increase the efficiency, and output of mitochondria! These are usually either co-enzymes that facilitate the process of making ATP, or are themselves metabolites in the process of making ATP.
These molecules like Co-enzyme Q10 (CoQ10), reduced glutathione (GSH), pyrroloquinoline quinone (PQQ), acetyl-L-carnitine (ALCAR), alpha-lipoic-acid, and many more are often found in every cell in our bodies like NADH, and are either directly or indirectly involved in making these processes in the mitochondria more efficient.

Is There Evidence for These Supplements?

This reduces oxidative stress and increases ATP output in he cells because they are able to work more efficicently. 
Some of these compounds have extensive research done on their supplemental use, and health effects. For example, glutathione alone has over 117,000 peer reviewed studies done on it! For more info on some of our favorite supplements to reduce ROS and free radicals click the images below.

Liposomal Glutathione
CoQ10 Gel Caps with BioPerine
Magnesium Chelate Powder for a Therapeutic Dose
DHA Brain Care by Vital Choice with Vitamin D3

 

Tags:dnadna damagefree radicalsroszombie cells
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Zach Nasr
Zach was on his way to being a doctor when a personal health crisis changed all of that. He decided that he wanted to create wellness instead of fight illness. He lost over a 100 lbs through functional nutrition and other natural healing protocols. He has since been sharing his knowledge of nutrition and functional medicine for the last 12 years as a health coach and health educator.

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“How to Feed a Brain is an important book. It’s the book I’ve been looking for since sustaining multiple concussions in the fall of 2013. I’ve dabbled in and out of gluten, dairy, and (processed) sugar free diets the past few years, but I have never eaten enough nutritious foods. This book has a simple-to-follow guide on daily consumption of produce, meat, and water.

I appreciate how Cavin writes about important concepts, such as leaky gut and glial cells, in a clear and concise manner.

There are a large number of people attempting to recover from brain injuries that are lacking the right information on nutrition. Thanks to Cavin and his team, we have this book now.

I look forward to eating my quality vegetables, proteins, and fats every day now as I know that they will help my brain to heal.

Cavin’s story is inspirational and worth a read on its own.”

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The very basic concept of good nutrition among all the conflicting advertisements and various “new”

“As a neuro-optometrist who cares for many brain-injured patients experiencing visual challenges that negatively impact the progress of many of their other therapies, Cavin’s book is a god-send! The very basic concept of good nutrition among all the conflicting advertisements and various “new” food plans and diets can be enough to put anyone into a brain fog much less a brain injured survivor! Cavin’s book is straightforward and written from not only personal experience but the validation of so many well-respected contemporary health care researchers and practitioners! I will certainly be recommending this book as a “Survival/Recovery 101” resource for all my patients including those without brain injuries because we all need optimum health and well-being and it starts with proper nourishment! Kudos to Cavin Balaster!”

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What an incredible journey for Cavin, from a predicted vegetative state, to an author and teacher, informing us how to
feed our brains to optimize our lives. Very informative book and well organized , and written so it is understandable. Love the charts. Thank you Cavin and thanks to your Mother who didn’t give up.

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One of this year’s very best health and wellness books!

“There are many health and wellness books being published daily. Do not miss the opportunity to read one of the best for this year: “How to Feed a Brain” by Cavin Balaster, a true expert on deep brain injury who writes from his personal experiences with a great sense of compassion and humanity.

You will not find a better treatment of this critically important subject. You need not have had brain injury to gain the superbly presented information Cavin provides.

For all of us who care about ourselves, friends and family – – this is a book to read and loan out…. but be careful “How to Feed a Brain” you may not get this excellent read returned!”

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Book that will change how you think about food!

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Great Resource-brain injury not required

“Cavin Balaster knows brain injury as well as any specialist. He survived a horrific accident and came out on the other side stronger than ever. His book, “How To Feed A Brain” details how changing his diet helped him to recover further from the devastating symptoms of brain injury such as fatigue and brain fog. Cavin is able to thoroughly explain complex issues in a simplified manner so the reader does not need a medical degree to understand. The book also includes comprehensive charts to simplify what the body needs and how to provide the necessary foods. “How To Feed A Brain” is a great resource for anyone looking to improve their health through diet, brain injury not required.”

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“I have had brain issues for many years. I purchased the Kindle version. I like the idea of reading Cavins book because he has lived through a terrible brain injury and has come back victorious.”

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But I do feel better in several ways that just might be related to…

“I cannot overstate how grateful I am to Cavin for having published this book (and launched his podcast) before I needed it. I am 3.5 months out from a concussion and struggling to recover that final 25% or so of my brain and function. I fully believe that diet and lifestyle can help heal many of our ills, and this book gives me a path forward right now. Gavin’s story is inspiring, and his book is well-researched and clearly written. I am a food geek and so innately understand a lot of his advice — I’m not intimidated by the thought of drastically changing my diet because I know well how to shop and cook for myself — but I so appreciate how his gentle approach and stories about his own struggles with a new diet might help people who would find it all daunting. I am in week 2 of following his advice (and also Dr. Titus Chiu’s BrainSave plan). It’s not an instantaneous miracle cure, but I do feel better in several ways that just might be related to this diet.”

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Love this book

“Love this book! Still reading and can’t wait to see what else I learn…and I am not brain injured! Cavin has already helped me to take steps to address my food sensitivity…seems to be helping and I am only on day 5! He has also helped me to help a family member who has suffered a stroke. Thank you Cavin, for sharing all your knowledge and hard work with us! This book is for anyone that wants to understand and implement good nutrition with all the latest research to back it up. Highly recommend!”

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The best / most practical book for TBI’ers

“Suffered a TBI or just want to improve, this book contains the information you need to blend into your life, and Cavin tells you how. Everything is backed up with scientific evidence. Implementation of this book will change / restore your outlook on life.”

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I love this book

“I love this book! As someone that deals with an autoimmune condition, I deal with sever brain fog. I’m currently in school and this has had a very negative impact on my learning. I have been looking for something like this to help my brain function better. This book has me thinking clearer, and my memory has improved. I’m eating healthier and overall feeling much better. This book is very easy to follow and also has some great recipes included.”

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- Jennifer Ramirez

Cavin’s Balaster’s How to Feed a Brain is one the best written health nutrition books that I have ever read

“I have a bachelors degree in Nutrition Science. Cavin’s Balaster’s How to Feed a Brain is one the best written health nutrition books that I have ever read. It is evident that through his personal journey with a TBI and many years of research Cavin has gained a great depth of understanding on the biomechanics of nutrition has how it relates to the structure of the brain and nervous system, as well as how all of the body systems intercommunicate with one another. He then takes this complicated knowledge and breaks it down into a concise and comprehensive book. If you or your loved one is suffering from ANY neurological disorder or TBI please read this book.”

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- Ashley Jean Flowers

Feed your brain – read this book

“The author’s story alone is a remarkable account of not just survival, but transcendence of a near-death experience. Cavin went on to become an advocate for survival and survivors of traumatic brain injuries, discovering along the way the key role played by nutrition. But this book is not just for injury survivors. It is for anyone who wants to live (and eat) well.”

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- David L. Butler

Beautiful inspiring story about relearning how to live after a traumatic experience

“Amazing book and extremely inspiring story. The author is a close friend of mine and we were reunited later in life due to traumatic life experiences. Truly demonstrates the beauty and nature of the human body and the ability to bounce back. If I could rate this 6 stars I would!!!!”

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- Sammy Morrison

Five Stars

“Great book!! Full of important information for everyone.”

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- Mar

Book is great, full of recommended micro nutrient and reason why…

“Book is great, full of recommended micro nutrient and reason why they are important to brain health. But it gets redudant over time when author tried to promote his website and his online shop frequently all over the book. But this is great book nonetheless.”

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- Vekit

Fistfuls of exciting brain foods to launch you plus feeding tube powerful nutrition implementation…

“In the hospital and ICU struggles, this book and Cavin’s experience are golden, and if we’d have had this book’s special attention to feeding tube nutrition, my son would be alive today sitting right here along with me saying it was the cod liver oil, the fish oil, and other nutrients able to be fed to him instead of the junk in the pharmacy tubes, that got him past the liver-test results, past the internal bleeding, past the brain difficulties controlling so many response-obstacles back then. Back then, the ‘experts’ in rural hospitals were unwilling to listen, ignored my son’s unexpected turnaround when we used codliver oil transdermally on his sore skin, threatened instead to throw me out, but Cavin has his own proof and his accumulated experience in others’ journeys. Cavin’s boxed areas of notes throughout the book on applying the brain nutrient concepts in feeding tubes are powerful stuff, details to grab onto and run with… hammer them!

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Five Stars

“Great read and info for anyone suffering from brain trauma.”

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- Laura-Florida

One of the best

“Cavin is a great man. A survivor… And a rock star.
I met him when I was 19, and re-met him later in life, after his accident. He still has this gorgeous understanding of the world that makes me believe in him, and always makes me listen to what he has to say.
When my mom had a stroke last year he was the first person I called. He had so much knowledge about what she was going though and totally understood what I was experiencing as well.
He was the first person I thought of, and hopefully the last I’ll need to.

You’re the best, Mr. B.”

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- Adrien Fox

An Enlightening Book For Anyone With A Brain

“In 183 pages, Cavin Balaster’s new book, How to Feed A Brain provides an outline and plan for how to maximize one’s brain performance. The “Citation Notes” provide all the scientific and academic documentation for further understanding. The “Additional Resources and Tips” listing takes you to Cavin’s website for more detail than could be covered in 183 pages. Cavin came to this knowledge through the need to recover from a severe traumatic brain injury and he did not keep his lessons learned to himself. This book is enlightening for anyone with a brain. We all want to function optimally, even to take exams, stay dynamic, and make positive contributions to our communities. Bravo Cavin for sharing your lessons learned!”

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- Chandini Bachman

His story changes lives…

“As a physical therapist with 30+ years of experience in treating neurological disorders such as traumatic brain injury, I simply could not believe it when Cavin told me the extent of his injuries. His story opened a new door to my awareness of the incredible benefits of proper nutrition, the power of attitude and community to heal anything we have arise in our lives Cavin is an inspiration and a true way-shower for anyone looking to invest in their health and well-being. No matter the state your brain is in, you will benefit from this cutting-edge information and be very glad (and entertained) that you read this fine work.”

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- Melanie Carlone

Total game-changer

“Following this way of eating has been a complete game-changer for me. I am 1 year post concussion and thought I had stalled in my recovery. Buy this book, follow the instructions, see RESULTS!”

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- Sharon Lori Parker

I wish I had this book when I suffered my…

“I wish I had this book when I suffered my TBIs 10 years ago, but never too late. Thank Cavin!”

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- SMack

My dog was too literal

“Fine book but grossly misunderstood by dog. She ate the pages & her brain is fine. This speaks to the virtue of book’s content.”

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- Lia Kass

Vital information

“The author is a remarkable and inspirational survivor of traumatic brain injury. His breakthrough recovery through nutrition and holistic health care demonstrates a radical new approach to healing the brain. This is vital information for health care providers and the public.”

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"Armchair Shopper"

Wonderful!

“Cavin has done an amazing job in all aspects of his life. Overcoming the horrific life threatening accident, and then going on to do whatever he can to help others with his contagious wonderful attitude. This book is an easy to understand fact filled manual for anyone, but especially those who are or are caregivers for a loved one with tbi. I also highly recommend his podcast series.”

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- Nancy

This book is a wonderful.

“This book is a wonderful, motivating reference for anyone who wants a healthy and sharp brain at any age.”

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- Ammon B.

An absolute must for autoimmune sufferers!

“I bought this book because I didn’t want a weightloss diet, but I wanted the most optimal gut/brain food I could find to help with an autoimmune. I subscribe to Cavin’s podcast and another newsletter for gut health which also recommended this book. Also, he’s a personal friend of mine who’s recovery I have witnessed firsthand. Thank you so much for all of the research and your continued dedication to not only help yourself, but for also helping others!”

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- Lauren L. Chemin

Well written, educational, and promotes positive lifestyle changes that can be made today!

“Cavin’s personal experience and humble writing to help educate, not only people who have suffered brain injuries, but anyone interested in the best nutritional advice for optimum brain function is a great introduction to proper nutrition filled with many recommendations of how you can make a changes to your diet immediately. This book provides amazing personal insight related to Cavin’s recovery accompanied with well cited peer reviewed sources throughout the entire book detailing the most recent findings around functional neurology!

I highly recommend this book for anyone interested in learning more about nutrition and how it can impact brain function! As well as anyone willing to challenge themselves TODAY with the recommendations throughout this book!”

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- Andrew Ritter

If you are looking to get the optimum performance out of your brain, get this book now!

“As a brain injury survivor that still deals with extreme light sensitivity, eye issues and other brain related struggles I have found a great diet is a key to brain health! Cavin’s book is a much needed guide to eating for brain health. While you can fill shelves with books that teach you good nutrition, Cavin’s book teaches you how to help your brain with what you eat. This is a much needed addition to the nutrition section! If you are looking to get the optimum performance out of your brain, get this book now! You won’t regret it.”

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- Ben

but I do feel better in several ways that just might be related to…

“I cannot overstate how grateful I am to Cavin for having published this book (and launched his podcast) before I needed it.”

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- Sara New Orleans, LA United States

We can take care of our brains

“I am nearly four years out from my traumatic brain injury and I have been through 100’s of hours of rehabilitation therapy. I have been surprised by how little attention is given to adequate nutrition for recovering from TBI. I’m always looking for further opportunities to recover and so this book fell into the right hands. Cavin outlines the science and reasoning behind the diet he suggests, but the real power in this book comes when he writes, “WE.” WE can give our brains proper nutrition. Now I’m excited to drink smoothies and eat breakfasts that look like dinners! I will recommend this book to my friends.

(I was given a complimentary copy of this book in exchange for an honest review.)”

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- Rachel J.

A must read for everyone’s health and wellness journey!

“Such an informative and inspiring read! Insight into how optimal nutrients improved Cavin’s own brain recovery make this knowledge-filled read compelling and relatable. The recommendations are easy to understand as well as scientifically-founded – it’s not another fad diet manual. The additional tools and resources provided throughout make it possible for anyone to integrate these enhancements into their nutritional repertoire. Looking forward to more from Cavin and Feed a Brain!!!!!!”

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- Amazon Customer

Excellent book if you want to be vibrant

“Excellent book if you want to be vibrant!!!! Everything you need to know to achieve excellent health overalll….not just your brain! The author’s amazing story from tragedy to good health really inspires me.”

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- Opinions on Everything

Awesome

“I wish I saw this book one year ago. Thanks, Dr. Deborah Zelinsky, for asking (me) to buy it. Thanks, Cavin, for making time to talk to me. I am so happy.”

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- Amazon Customer

Five Stars

“Very interesting… “back-to-basics” … the first book I read to the end in years.”

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- Kristin

Very informative

“I enjoyed this book. It was full of practical information. It was easy to understand. I implemented some of the ideas in the book and they have made a positive impact for me. Not only is this book a wealth of knowledge it helps you think outside the box and piece together other ideas to research and helps you understand more about TBI and the way food might help you mitigate symptoms.”

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- Dixie

Excellent resource for people wanting to feed their brains!

“Cavin’s story is so inspirational and moving. As a practicing Functional Neurologist that specializes in Post-Concussion Syndrome and having suffered multiple head injuries myself, the information that Cavin has put together based on his experiences is totally spot on.

I love seeing such cutting-edge information on brain health out there in the world. Highly recommended!”

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- Titus Chiu

I prefer to read about people who have lived recovery.

“I have had brain issues for many years. I purchased the Kindle version. I like the idea of reading Cavins book because he has lived through terrible brain injury and has come back victorious.”

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- T. Riley

Must read

“Bought this to learn the best way to feed my son after he sustained a hypoxic brain injury. This book is very informative and the author Cavin is amazing. He had created a lot of resources that are very helpful.”

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- Steele Family

A book that keeps on feeding

“Cavin, you are phemomenal! An incredulous journey of a near death accident scripted by an incredible man who chose to share his knowledge of healing his own broken brain. I requested our public library purchase your book because everyone, those with and without brain injuries, should have access to YOUR brain and this book. Thank you for your legacy to mankind!”

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- Fasting Filly

Worth the read

“Cavin Balaster is an amazing man with an amazing story. He is an inspiration and his book is a good resource for everyone who has a brain.”

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- T.

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