Cardiovascular Disease Treatment

First 8 Weeks:

  • Weekly IM injections of
    • 1 g – Magnesium (magnesium sulfate) for eight weeks,
  • Daily oral supplementation:
    • 2g 2x/day – Vitamin C (ascorbic acid) 
    • 100mg/day – Vitamin E (alpha-tocopherol)
    • Recommended Dose – B complex
    • 7.5 mg 2x/day – B6 (methylfolate) 
    • 22mg 1x – Zinc (zinc glycinate amino acid chelate)

After 8 Weeks:

  • Weekly IV injections (replacing IM injections), consisting of: 
    • 5.0 mL – Magnesium chloride hexahydrate 20% (magnesium)
    • 1.0 mL – Hydroxocobalamin 1,000 mcg/mL (B12)
    • 1.0 mL – Pyridoxine hydrochloride 100 mg/mL (B6)
    • 1.0 mL – Dexpanthenol 250 mg/mL (B5)
    • 1.0 mL – B complex 100 (B complex)
    • 0.2 mL – Trace mineral preparation (MTE-5 containing: zinc, copper, chromium, selenium, and manganese).

“All ingredients [except for the trace minerals] are drawn into one syringe, and 8-20 mL of sterile water (occasionally more) is added to reduce the hypertonicity of the solution… Trace minerals should not be mixed in the same syringe with the components of the Myers’, as doing so often causes formation of a precipitate.

After gently mixing by turning the syringe a few times, the solution is administered slowly, usually over a period of 5-15 minutes (depending on the doses of minerals used and on individual tolerance), through a 25G butterfly needle.

Low doses are often given to elderly or frail patients, and to those with hypotension. Doses for children are lower than those listed, and are reduced roughly in proportion to body weight.”

Trace minerals should not be mixed in the same syringe with the components of the Myers’, as doing so often causes formation of a precipitate.

Occasionally, trace minerals were included as part of a nutrient infusion. The usual dose was 0.2-0.5 mL of MTE-5… The preparation [of MTE-5] was diluted six-fold and administered over a period of 1-2 minutes in a separate syringe at the end of the Myers’ push… when giving trace minerals by IV push, very small doses are used.

Continue intravenous therapy and eventually reduce to every other week.

 

Research:

Intravenous Nutrient Therapy: the “Myers’ Cocktail”

(Access the full article by clicking here)

  • Why this must be IV:

    • “Intravenous administration of nutrients can achieve serum concentrations not obtainable with oral, or even intramuscular (IM), administration. For example, as the oral dose of vitamin C is increased progressively, the serum concentration of ascorbate tends to approach an upper limit, as a result of both saturation of gastrointestinal absorption and a sharp increase in renal clearance of the vitamin.”
    • “In addition to having direct pharmacological effects, IV nutrient therapy may be more effective than oral or IM treatment for correcting intracellular nutrient deficits. Some nutrients are present at much higher concentrations in the cells than in the serum.”

    • Vitamin C

      • “The highest serum vitamin C level reported after oral administration of pharmacological doses of the vitamin is 9.3 mg/dL. In contrast, IV administration of 50 g/day of vitamin C resulted in a mean peak plasma level of 80 mg/dL.
      • “… an antiviral effect of vitamin C has been demonstrated at a concentration of 10- 15 mg/dL,4 a level achievable with IV but not oral therapy.”

    • Magnesium

      • “Intravenous administration of magnesium, by producing a marked, though transient, increase in the serum concentration, provides a window of opportunity for ailing cells to take up magnesium against a smaller concentration gradient.”
      • “Magnesium ions promote relaxation of both vascular and bronchial smooth muscle – effects that might be useful in the acute treatment of vasospastic angina and bronchial asthma, respectively. It is likely these and other nutrients exert additional, as yet unidentified, pharmacological effects when present in high concentrations.”

 

“Cardiovascular Disease Case #5:

  • [Presentation:]

    • A 79-year-old man was seen at home in end-stage heart failure, after having suffered four myocardial infarctions.
    • During the previous 12 months, spent mostly in the hospital, he had become progressively worse
    • His ejection fraction had fallen to 19 percent…
    • His body weight had declined from 171 pounds to a severely cachectic 113 pounds.
    • He was confined to bed and required supplemental oxygen much of the time.
    • He also had severe peripheral occlusive arterial disease, which had resulted in the development of gangrene of six toes.
    • A peripheral angiogram revealed complete occlusion of both femoral popliteal arteries, with no detectable blood flow to the distal extremities.
    • Two independent vascular surgeons had recommended bilateral above the-knee amputations to prevent development of septicemia.

  • [Treatment]

    • He was treated with weekly IM injections of magnesium sulfate (1 g) for eight weeks, and prescribed oral supplementation with vitamins C and E, B complex, folic acid, and zinc.
    • The magnesium injections appeared to reduce the pain in his gangrenous toes considerably, with the benefit lasting about five days each time.
    • Six weeks after the first injection, his ejection fraction had increased from 19 percent to 36 percent and he no longer required supplemental oxygen.

  • After eight weeks

    • IM injections were replaced by weekly IV injections, consisting of
      • 5 mL magnesium,
      • 1 mL each of B12, B6, B5, and B complex,
      • and a low-dose (0.2 mL) trace mineral preparation (MTE-5 containing: zinc, copper, chromium, selenium, and manganese).
    • After a total of 18 months, his weight had increased from 113 to 147 pounds, which was remarkable as cardiac cachexia is generally considered to be irreversible.
    • … the gangrenous areas on his toes had sloughed and been replaced almost entirely by healthy tissue.
    • … Of the handful of other patients with angina or heart failure who received IV or IM injections of magnesium (with or without B vitamins), all showed significant improvement.”

The Modified Myer’s is Also Used for Other Conditions

(asthma attacks, acute migraines, fatigue (including chronic fatigue syndrome), fibromyalgia, acute muscle spasm, upper respiratory tract infections, chronic sinusitis, and seasonal allergic rhinitis)

“the most commonly used regimen has been 4 mL magnesium, 2 mL calcium, 1 mL each of B12, B6, B5, and B complex, 6 mL vitamin C, and 8 mL sterile water.”